Facebook
  • Azelaic Acid
  • Azelaic Acid
  • Azelaic Acid
  • Azelaic Acid
  • Azelaic Acid
  • Azelaic Acid

Azelaic Acid

No.Azelaic Acid
Chemical Name: Azelaic Acid CAS No.: 123-99-9 Appearance: White Powder Molecular Fomula: C9H16O4
  • Azelaic Acid
  • Azelaic Acid
  • Azelaic Acid
  • SPECIFICATION
  • Shipping Methods
  • FAQs

Product Description


Azelaic acid inhibits or kills anaerobic and aerobic bacteria on the skin. In vivo test shows that topical application of azelaic acid cream for 2 to 3 months can significantly reduce the number of bacteria in the skin and Propionibacterium in the hair follicle, indicating that this product has direct antibacterial effect. In addition, topical application of azelaic acid reduces the composition of free fatty acids and lipids on the skin surface. It shows anti-keratinization effect on the skin of normal people or acne patients, and its principle of action is mainly due to reducing the synthesis of filamentous keratin, thereby reducing the hyperkeratosis of hair follicles. Azelaic acid selectively acts on abnormal melanocytes and inhibits their overactivity. Therefore, topical application of azelaic acid for a long time can reduce the production of skin melanin in patients with age spots. Azelaic acid also has anti-cell proliferation and anti-cytotoxic effects, and its principle of action is mainly through the destruction of mitochondrial respiratory pathways and cellular DNA synthesis.
 

Product Name Azelaic Acid
Appearance White Powder 
Specification 99%
CAS 123-99-9
Package 1kg/aluminum foil bag; 25kg/drum
Sample Available
Storage Dry Place
Shelf life 2 Years

Product Function


1. Can be used for freckle and acne removal at the same time

2. It can be used in cosmetics and medicines at the same time.

3. It has excellent functionality (as a raw material for freckle and acne removal in the authoritative dermatological pharmacopoeia), but it has very good safety.

4. The whitening effect of ordinary skin is not very obvious, but it has a very obvious effect on severe pigmentation, such as freckles, chloasma, melanosis, etc.

5. Very stable (no unsaturated double bonds in the molecular structure), different from general functional raw materials

Azelaic acid,  has a chemical structure of HOOC(CH2)7COOH, which is a naturally occurring saturated dicarboxylic acid containing nine carbon atoms.

Product Application


1. Dissolving, dispersing and adding concentration

The biggest inconvenience in application of azelaic acid is that it is insoluble in water and oil under normal conditions. In the past medical applications of azelaic acid were dispersed in the emulsification system with a concentration ratio of 10-20%, which was basically completely insoluble, which was not conducive to the full play of the effect of azelaic acid, and also made the emulsion rough and not delicate. At present, there are cosolvents with very high safety and good solubility, cosol, and the solubility is greatly increased by dozens to hundreds of times. There is no detailed medical clinical report on how much the increase in solubility improves the effect. In the past, it was mostly used in the concentration of 15-20% for acne, and 10-20% in clinical medicine for freckle removal; there are also low-concentration applications (Allergan 1% lotion in the United States). Due to the use of solubilizing and synergistic agents, the solubility is greatly improved. At the same time, because a variety of compound synergies are often used in cosmetic freckle removal, it can be used at a concentration of about 2-5%; the concentration of acne removal can be used at about 4-10%. The optimal addition amount of azelaic acid needs to be explored in application.​​

2. Irritability and pH

The irritation of azelaic acid was felt in the past, mainly because the purity of azelaic acid was not high (usually 90%) and the pH value was not adjusted. Azelaic acid is slightly soluble in water, with a pH value of about 3.6. For acne removal, there is a certain tingling sensation due to skin trauma. It is best to adjust the pH value to about 5.5; for acne removal, weak acidity causes slight keratin loosening. Conducive to the absorption of active ingredients, the PH value can be about 4.5.

 

More Information

  Whitening Agents
Browse our wide selection active whitening ingredients
 
  Abstract
Skin whitening products are commercially available for cosmetic purposes in order to obtain a lighter skin appearance. They are also utilized for clinical treatment of pigmentary disorders such as melasma or postinflammatory hyperpigmentation.
   
Whitening agents act at various levels of melanin production in the skin. Many of them are known as competitive inhibitors of tyrosinase, the key enzyme in melanogenesis.
 
     
  Cas No. Product Name   Cas No. Product Name  
  183476-82-6 VC-IP/Ascorbyl Tetraisopalmitate   1077-28-7 A-Lipoic Acid  
  84380-01-8 Alpha Arbutin   305-84-0 Carnosine  
  497-76-7 Beta Arbutin   497-30-3 Ergothioneine  
  53936-56-4 Deoxyarbutin   175357-18-3 Undecylenoyl Phenylalanine/Sepiwhite MSH  
  501-30-4 Kojic Acid   331-39-5 Caffeic acid  
  79725-98-7 Kojic Acid Dipalmitate   86404-04-8 3-o-ethyl ascorbic acid  
  123-31-9 Hydroquinone   103-16-2 Monobenzone  
  1105025-85-1 Dimethymethoxyl Chromanyl Palmitate   114040-31-2 Magnesium Ascorbyl Phosphate  
  1197-18-8 Tranexamic Acid   66170-10-3 Sodium Ascorbyl Phosphate  
  922165-31-9 Neosolue-aqulio   123-99-9 Azelaic Acid  
  96702-03-3 Ectoin   84696-21-9 Hydrocotyle Asiatica Extract  
  83923-51-7 Dimethylmethoxy Chromanol   90-64-2 Mandelic acid  
  79-14-1 Glycolic Acid   73-31-4 Melatonin  
  7402-28-0 1,4-Dipropionyloxybenzene   152312-71-5 Potassium 4-Methoxysalicylate/4-MSK  
  1077-28-7 A-Lipoic Acid   129499-78-1 Ascorbyl Glucoside/AA2G  
  305-84-0 Carnosine   69-72-7 Salicylic Acid/BHA  
  497-30-3 Ergothioneine   - Alpha Hydroxy Acid/AHA  
  175357-18-3 Undecylenoyl Phenylalanine/Sepiwhite MSH   83-86-3 Phytic acid  
  331-39-5 Caffeic acid   - Snow White  
  98-92-0 Niacinamide   - Giga White  
  90082-87-4 Plum, ext   - Glabridin  
  36062-04-1 Tetrahydrocurcumin   36062-04-1 Tetrahydrocurcuminoids  
  85-27-8 Symwhite 377/Phenylethyl Resorcinol   68797-35-3 Dipotassium Glycyrrhizinate  
  922165-31-9 Neosolue-aqulio   19771-63-2 Procysteine  
 
More Information: 

 

 

Hot tags: 

Shipping Policy

 

Learn about our shipping methods for international cosmetic ingredients, plant extract and supplements orders. Our international carriers include FedEx, UPS, and DHL Express. Choose a shipping option that best fits your budget and needs. However, in some cases we reserve the right, without notice, to change the shipping service on your order due to high value. UPS will be switched to FedEx Ground and a signature upon delivery will be required. All orders are shipped from our warehouse in China.

 

International Shipping

We ship to over 150 countries worldwide and have over 4 years of experience dealing with international shipping documentation. Please note that shipping charges may vary from the amount indicated by the automatic shipping calculator since the weight calculated on the website may differ from the actual package weight due to the packaging material. There is no handling fee for all international orders.

Customs fees, VAT, or value added tax, and sales tax are typically charged by the government of your country and must be paid by the customer once the package arrives. We cannot determine what these fees will be. We recommend that you check with your local customs office or post office for details on how these charges are assessed and applied. For customs clearance, a customs broker is usually needed who may charge you a brokerage fee. Packages may be held up in customs for a few days and will delay delivery.
 

  • FedEx International Economy: delivers in five business days to more than 220 countries for packages up to 150 pounds. Includes tracking. Extra services include broker service and customs cleared service. Please provide your FedEx account number in the "Shipping Instructions" section of your order if you want to have it shipped on your account. The prepaid shipping cost will be refunded.
  • FedEx International Priority: delivers in one to three business days and two business days for major cities in Europe. This shipping option is available for more than 220 countries for packages up to 150 pounds. Includes tracking. Extra services include broker service, third party consignee, and customs cleared service. Please provide your FedEx account number in the "Shipping Instructions" section of your order if you want to have it shipped on your account. The prepaid shipping cost will be refunded.


  • Worldwide Expedited: offers customs-cleared, day-definite delivery to more than 220 countries and territories in two to five business days.

  • Worldwide Express: this service offers guaranteed delivery in 1-3 business days depending on the destination. Service is available in 185 countries and territories.

  • Worldwide Saver: offers guaranteed afternoon delivery in 1-3 days for your international shipments. Next business day delivery to Canada, two business days to Europe and Latin America, and two or three business days to Asia. Service is available in 215 countries.


 

  • DHL Express Worldwide: DHL offers exclusively express shipping services around the globe. Slower shipping services that take longer than four to five days are not available with DHL. The Express Service is a time-sensitive service with proactive delivery notification available on request. Delivers by the end of the next possible business day. Intercontinental shipments usually take three days.

01. How to contact with us?

         Online service:by Trademanager, Skype,Email
         You can choose your Interested products and send inquiry to us.
         Call us without any hesitation.

02. How to confirm the products quality before placing orders?

         We will offer you our products specification standard to you,and we test every batch of our product by HPLC.UV,GC AND TLC AND etc. We also cooperate with independent third party lab such as SGS,PONY etc.
         FREE SAMPLES of some products can be sent on request,only need to pay the shipping cost  or arrange a courier to us and take the samples. Send us your products specifications and requests, we will produce for you.

03. How to make order & payment?

         We can accept payment by TT,WESTERN UNION,Escrow,Paypal,L/C

04. How to pack and storage?

         Packing:1kg/Aluminium Floil bag with Carton outside.  25KG/Fiber drum with double PE BAGS INSIDE.
         Storage:Store in cool & Dryplace,keep away from light and heat.

05. How to ship and delivery?

         Transit could be DHL,UPS,TNT,FEDEX,EMS.For mass orders,it will be ship by air or sea.

06. Our reture service policy

         We offer an full money back guarantee,if you are not 100% satisfied with our products,return all goods back to us within 60 days and we will fully refund your money.