Supply Herbal Extract Polydatin | Health Care Material Giant Knotweed Rhizome Extract
Polydatin is a precursor of stilbene glucoside and trans-resveratrol. It has been found in grape vines and has a variety of biological activities. 1,2,3 It scavenges DPPH free radicals and inhibits copper-induced lipid peroxidation (IC50s = 198 and 19.1 µM, respectively). 1 Polydatin inhibits the proliferation of Caco-2 colon cancer cells and induces cell cycle arrest in the S phase. 2 Reduce infarct size, cardiomyocyte fibrosis, and apoptosis in a mouse model induced by myocardial ischemia-reperfusion injury. When administered at a dose of 40 mg/kg per day, the coronary artery is occluded through the left anterior descending artery (LAD).