Alpha Arbutin

Item No.: Alpha Arbutin
CAS No.:84380-01-8
Appearance:White Powder
Usage:Cosmetic Raw Materials, Hair Care Chemicals
Apperance:White Powder
Documents available:COA

Best Alpha Arbutin Manufacturers | Supplier with Wholesale Price - Greenway Biotech

Arbutin is a hydroquinone glycoside compound, the chemical name is 4-Hydroquinone-alpha-D-glucopyranoside, which exists in bearberry, bilberry and other plants. It is a new non-irritating, non-allergic and highly compatible natural whitening active substance from Chemicalbook. There are two structural and functional functional groups in the molecular structure of arbutin: one is a glucose residue; the other is a phenolic hydroxyl group. The physical state of α-arbutin is white to light gray powder, which is easily soluble in water and ethanol.

 Product Name:  Alpha Arbutin
 Appearance:   White Crystalline Powder
 Specification:   99% HPLC                                 
 Cas No.:  84380-01-8
 Test method:  HPLC
 Partical size:  100% pass 80 mesh
 Shelf Life:  2 Years


Product Information

Product Name Alpha Arbutin 
English synonyms Alpha Arbutin Powder; 4-hydroquinone-alpha-d-glucopyranoside; alpha-arbutin; a-Arbutin; HydroquinoneO-alpha -D-Glucopyranoside; 4-Hydroxyphenyla-D-gChemicalbooklucopyranoside;(2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL;4-hydroxyphenylalpha-D-glucopyranoside
Molecular formula: C12H16O7
Molecular weight: 272.25
EC Number 209-795-0

Melting point 195-196°C
Boiling point 561.6±50.0°C(Predicted)
Density 1.556±0.06g/cm3(Predicted)
Storage conditions 2-8°C
Solubility DMSO(Slightly),Methanol(Slightly)
Appearance Solid
Color White to Off-White
Effect α-Arbutin has a good therapeutic effect on scars caused by ultraviolet burns, and has good anti-inflammatory, repairing and whitening effects. Can inhibit the production and deposition of melanin, remove pigmentation and freckles.
Mechanism The whitening mechanism of α-arbutin directly inhibits the activity of tyrosinase, thereby reducing the production of melanin, rather than reducing the production of melanin by inhibiting cell growth or tyrosinase gene expression. Since α-arbutin is a more efficient and safer whitening active substance, many cosmetic companies at home and abroad have used α-arbutin instead of β-arbutin as a whitening additive.
Application Alpha-arbutin is a chemical, similar to arbutin, that inhibits the production and deposition of melanin, and removes pigmentation and freckles. Studies have shown that arbutin can inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase is better than that of arbutin. Alpha-arbutin can be used in cosmetics as a whitening agent.
Purification and Identification The samples obtained by the reaction were first extracted with ethyl acetate, then extracted with n-butanol, evaporated to dryness by a rotary evaporator, and then centrifuged. The supernatant was analyzed by HPLC and compared with α-arbutin standard Compare the HPLC chromatogram of the product, compare whether the sample and α-arbutin have the same retention time of Chemicalbook, and preliminarily infer whether the sample contains α-arbutin. The product after extraction and purification was identified by the positive ion mode of LC-ESI-MS/MS. The relative molecular mass of the α-arbutin product is compared with the relative molecular weight of the α-arbutin standard to determine whether the product is α-arbutin.

Certification of Analysis

Items Specifications Results
Appearance White or Off-white Powder White Powder
pH value 5.0-7.0 6.05
Melting point 202℃-210℃ 204.8℃-205.6℃
Specific optical rotation +175.0°+185.0° +179.4°
Loss on drying ≤1.0% 0.13%
Transmittance ≥95.0% 99.0%
Hydroquinone(HPLC) 10ppm <10ppm
Heavy metals ≤10ppm <10ppm
Arsenic ≤2ppm <2ppm
Lead(Pb) 1ppm <1ppm
Residue on ignition ≤0.5% 0.05%
Assay(HPLC) ≥99.5% 99.98%
Total plate count ≤1000 CFU/g 20CFU/g
Yeast&Mold ≤100 CFU/g 10CFU/g
E.Coli Not detectable Not detectable
Staphylococcus aureus Not detectable Not detectable
Pseudonmonas aeruginosa Not detectable Not detectable
Conclusion The product conforms to standard of Q/AHH012

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Certificate of Analysis | Alpha Arbutin Powder

Product Info | Alpha Arbutin


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