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Effects and uses of phenoxyethanol
詳細



  Basic Information
 
Phenoxyethanol:  also known as ethylene glycol monophenyl ether, phenyl cellosolve.

This product is a colorless slightly viscous liquid with aromatic odor and burning odor. It is miscible with water and polar organic solvents such as ethanol, propanol and propylene glycol. It has excellent solubility, can be dissolved with different types of products, and can be used to solubilize a variety of raw materials and active ingredients. Slightly soluble in water, easily soluble in ethanol, ether and sodium hydroxide solution. Can dissolve grease, natural resin, alkyd resin, cellulose acetate, ethyl cellulose, nitrocellulose and polyvinyl acetate, etc. It is stable in acid or alkali, has the chemical properties of primary alcohol, and is heated with zinc chloride to generate oxaindan by ring-closure reaction. Has broad-spectrum antibacterial activity and is used in combination with other active ingredients to enhance the activity of other antibacterial agents. A very stable molecule over a wide pH and temperature range, its activity is used over a wide pH range. The inhibitory concentration was 0.06% to 1.00%. Melting point 14 ℃, boiling point 244.9 ℃, flash point 107 ℃.

  Storage and use precautions

This product should be stored in an airtight container at room temperature in a well-ventilated, dry and cool place. During transportation, it should be lightly loaded and unloaded, and no impact should be allowed. This product shows no signs of instability when stored at an ambient temperature of 50°C for up to 12 months. The shelf life is 24 months under normal storage conditions.

  Function and use
 
Phenoxyethanol has good solubility and miscibility, and is often used as a diluent for fragrances, an ideal solvent for parabens, a better solvent and penetration aid for hair dyes and nail polish pigments. Solvents and modifiers for inks, ballpoint pen oils, penetrants for ink pads. Phenoxyethanol has specific bacteriostatic activity against Pseudomonas aeruginosa, and has bacteriostatic effect on both Gram-positive and negative bacteria. Because of its considerable solubility in water, white mineral oil, isopropyl palmitate and other cosmetic components. In addition, it has high efficiency and broad spectrum, low toxicity (rat oral power LD50=1260mg/kg) and no allergic irritation (2.2% aqueous solution is not irritating to the skin). Therefore, it is widely used in cosmetic creams and shampoos. Phenoxyethanol is also an important surgical drug and is often used for superficial infections such as skin wounds, burns, and scalds. and the treatment of abscesses and abscesses. The clinical effect is excellent.

Phenoxyethanol has a high boiling point and low volatility, and is used as a solvent for penetrating stamping, marking, pad and ballpoint pen inks. It is often used in combination with benzyl alcohol to improve performance. It is an ideal solvent for cellulose acetate, resins, dyes, photosensitive materials, etc. It is used as a textile auxiliary for printing pastes. Phenoxyethanol is a gas chromatographic stationary liquid and a standard for chromatographic analysis. It has bactericidal effect and is a hypoallergenic, high-efficiency, broad-spectrum disinfectant and preservative. Fragrance fixative (for soap and cosmetics), diluent, and also used as anesthetic for fish to calm fish, reduce activity, reduce oxygen consumption, reduce the excretion of carbon dioxide and ammonia gas, and facilitate transportation, induction of labor and other operations. conduct.

Phenoxyethanol is used in organic synthesis raw materials, coating monomers and synthetic plasticizers. Its esters are perfume fixatives, fungicides and insect repellants. Phenoxyethanol glycerol ear drops for Pseudomonas aeruginosa otitis media.

  Identify
 
Take 2.5 g of this product, put it in a 100-ml conical flask, add 25 ml of 10% sodium hydroxide solution to dissolve, add 8 ml of benzoyl chloride test solution, seal it, shake it for 15-20 minutes, and a white precipitate will appear. , filtered, the precipitate was washed with a small amount of distilled water, recrystallized with alcohol, and after drying, the melting point was about 64 °C.




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More Details:

Mild Preservative - Phenoxyethanol
Effects and uses of phenoxyethanol
Is phenoxyethanol bad for the skin?
Certificate of Analysis - 2-Phenoxyethanol




 

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